Clinical Trial Teams

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Clinical trial for dry mouth funded by "Innovation in Oral Care Award" by IADR/GSK

The dry-mouth clinical trial team from the Georgia Regents University (formerly Medical College of Georgia), College of Dental Medicine, is using our MIghTeaFlow formula lozenge to treat dry mouth.

Clockwise from left to right: Dr. Scott De Rossi, Dr. Kalu Ogbureke, Dr. Douglas Dickinson, Bob Wilson (dental student), Dr. Stephen Looney, Gina Hanafi (dental student), Dr. Stephen Hsu, and Dr. Jaisri Thoppay.

For more information on each member, please visit the College of Dental Medicine’s website at  http://www.gru.edu/dentalmedicine/

 

 

 

HUMAN TRIALS  

  • Phase I clinical trial at Mayo Clinic found that green tea catechins were well tolerated even at the dose of 4 grams/day. Shanafelt et al, J Clin Oncol. 2009 Aug 10;27(23):3808-14
  • A new published data from a 2-year Phase II clinical trail completed at  the Oral Health and Diagnostic Sciences Department of the College of Dental Medicine of the Georgia Regents University (formerly Medical College of Georgia), supported by the International Association for Dental Research

         Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 2014. 118:447-454
       
 ​Phase II Clinical Trial of Natural Formulation Containing Green Tea Catechins for Xerostomia
        Scott DeRossi1, Jaisri Thoppay2, Douglas Dickinson3, Stephen Looney1, Mary Stuart4, Kalu Ogbureke5, and Stephen Hsu1*
 
        1Georgia Regents University, Augusta, GA,  2University of Pennsylvania, Bryn Mawr, PA,  3DENTAC, US Army, Fort Gordon, GA,
        4Tingay Dental Clinic, Fort Gordon, GA,  5University of Texas School of Dentistry, Houston, TX  *Corresponding Author
        
        This Clinically proven MIGHTEAFLOW natural Green Tea with Xylitol formulation that:

          ·Naturally increases one’s own saliva flow by up to 400%
          ·Increases salivary pH from acidic to neutral (neutral pH helps protect against tooth decay and enamel erosion)
          ·Contains powerful antioxidants from green tea and the bacteria inhibiting natural sweetener Xylitol. Clinical trials have shown Xylitol alone does not help saliva flow.

  • For more information, please visit our technology web page.